Format

Send to

Choose Destination
See comment in PubMed Commons below
Lancet. 2003 Jan 25;361(9354):323-31.

Primary brain tumours in adults.

Author information

1
Fédération de Neurologie Mazarin, G H Pitié-Salpêtrière, 75013, Paris, France.

Abstract

The most frequent primary brain tumours in adults are gliomas and primary CNS lymphomas. In gliomas, molecular genetic analysis plays an increasing part in classification and treatment planning, a feature well illustrated by the chemosensitive oligodendrogliomas. Unfortunately, management of glioblastoma is still mainly palliative. Incidence of primary CNS lymphoma has increased strikingly in the past 20 years; substantial progress has been achieved in patients who are immunocompetent with the addition of methotrexate-based chemotherapy to radiotherapy, but the potential neurotoxic effects of this combination in elderly patients is worrisome.

PMID:
12559880
DOI:
10.1016/S0140-6736(03)12328-8
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center