Reimplantation of autoclaved or irradiated cortical bones invaded by soft tissue sarcomas

Anticancer Res. 2002 Nov-Dec;22(6B):3685-90.

Abstract

Background: Bone defects after excision of malignant bone and soft tissue tumors are usually reconstructed by autogenous bone grafting or allografting.

Patients and methods: We treated 2 patients who had soft tissue sarcomas with bone involvement, the first by excision and reimplantation of the hemicortical autogenous cortical bone graft after autoclaving and the second with intraoperative irradiation.

Results: In both patients, postoperative follow-up radiographic studies showed incorporation of the implanted bones into the host bones within 12 months. Biopsy of the implanted bone performed 3 years after surgery showed many viable osteocytes, and blood vessel invasion into Harversian canals. No complications regarding the reconstructive techniques were observed during the postoperative period.

Conclusion: The reimplantation of autogenous cortical bones after autoclaving or irradiation is a useful reconstructive method for partial bone defects in soft tissue tumor surgery.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Bone Neoplasms / surgery*
  • Bone Transplantation / methods*
  • Female
  • Humans
  • Plastic Surgery Procedures / methods*
  • Sarcoma / pathology
  • Sarcoma / surgery*
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / surgery*
  • Tibia / pathology
  • Tibia / radiation effects
  • Tibia / surgery*