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Crit Care Med. 2003 Jan;31(1):80-3.

Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis.

Author information

1
Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona College of Medicine, Tucson, USA.

Abstract

OBJECTIVE:

To describe the incidence of clinical deep venous thrombosis associated with femoral central venous catheters (CVC-DVT) in children with diabetic ketoacidosis (DKA).

DESIGN:

Retrospective case-matched control series.

SETTING:

Pediatric intensive care units of two university-affiliated hospitals.

PATIENTS:

All eight pediatric DKA patients with femoral central venous catheters between 1998 and 2001, and 16 age-matched control patients with femoral central venous catheters and circulatory shock.

INTERVENTIONS:

None.

MEASUREMENTS AND MAIN RESULTS:

The records of all children with DKA and the control patients were reviewed. CVC-DVT was defined as persistent ipsilateral leg swelling after removal of a femoral central venous catheter. Control patients with coagulopathies, thrombocytopenia, cancer, and hyperglycemia were excluded. Four of eight patients with DKA developed CVC-DVT compared with none of the 16 control patients (p = .007, Fisher's exact test). All four patients with DKA and CVC-DVT were <3 yrs old. Doppler ultrasound examination was performed on three of the four patients with clinical CVC-DVT, confirming the diagnosis in each case.

CONCLUSIONS:

This study suggests that young children with DKA have an increased incidence of clinical DVT associated with the placement of femoral central venous catheters.

[Indexed for MEDLINE]

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