Abstract
Resorcinolic lipids were isolated from the root extracts of Sorghum bicolor and identified as 4,6-dimethoxy-2-[(8'Z,11'Z)-8',11',14'-pentadecatriene]resorcinol (4), 4-methoxy-6-ethoxy-2-[(8'Z,11'Z)-8',11',14'-pentadecatriene]resorcinol (5), and 4-hydroxy-6-ethoxy-2-[(10'Z,13'Z)-10',13',16'-heptadecatriene]resorcinol (6). Compounds 4 and 5 inhibited photosynthetic oxygen evolution (IC50 0.09 and 0.20 microM, respectively). Compound 4 could not be enzymatically converted to a quinone, suggesting that the quinone moiety is not required for its photosystem II inhibitory activity. Compounds 5 and 6 are reported for the first time.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Algorithms
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Chlorophyll / metabolism
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Germination / drug effects
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Inhibitory Concentration 50
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Lactuca / drug effects
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Light-Harvesting Protein Complexes
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Lipids / chemistry
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Lipids / isolation & purification*
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Lipids / pharmacology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Photosynthesis / drug effects*
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Photosynthetic Reaction Center Complex Proteins / chemistry
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Photosynthetic Reaction Center Complex Proteins / metabolism*
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Photosystem II Protein Complex
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Plant Roots / chemistry
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Poaceae / chemistry*
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Quinones / metabolism
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Resorcinols / chemistry
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Resorcinols / isolation & purification*
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Resorcinols / pharmacology
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Stereoisomerism
Substances
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Light-Harvesting Protein Complexes
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Lipids
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Photosynthetic Reaction Center Complex Proteins
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Photosystem II Protein Complex
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Quinones
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Resorcinols
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Chlorophyll