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Heart Vessels. 2002 Dec;17(2):57-60.

Postoperative changes in angiographically normal saphenous vein coronary bypass grafts using intravascular ultrasound.

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Cardiovascular Division, Osaka Police Hospital, 10-31 Kitayama-cho, Tennoji-ku, Osaka 543-0035, Japan.


We examined the process of vessel wall thickening in angiographically normal saphenous vein grafts (SVGs) using intravascular ultrasound. Fifteen SVGs were studied in the early stage (within 1 month postoperatively) and 14 SVGs in the late stage (over 6 months postoperatively). Lumen cross-sectional area (CSA) and vessel CSA were measured. Vessel wall area (VWA) was calculated and %VWA was defined as VWA / vessel CSA. Vessel CSA, VWA, and %VWA were significantly larger in the late stage than in the early stage (28.8 vs 21.6 mm(2), 15.8 vs 5.3 mm(2), 55.7% vs 24.9%, respectively) and lumen CSA was smaller in the late stage (12.8 vs 16.2 mm(2)). VWA correlated with vessel CSA, but not with lumen CSA. The time course of %VWA showed that %VWA in the late stage was a plateau state. From these findings, we concluded that the wall thickening process in SVGs begins within 6 months postoperatively and is accompanied by compensatory vessel enlargement.

[Indexed for MEDLINE]

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