Format

Send to

Choose Destination
See comment in PubMed Commons below
Trends Neurosci. 2003 Feb;26(2):65-72.

Memory traces unbound.

Author information

1
Department of Psychology, McGill University, Montreal, Quebec, Canada H3A 1B1. nader@hebb.psych.mcgill.ca

Abstract

The idea that new memories are initially 'labile' and sensitive to disruption before becoming permanently stored in the wiring of the brain has been dogma for >100 years. Recently, we have revisited the hypothesis that reactivation of a consolidated memory can return it to a labile, sensitive state - in which it can be modified, strengthened, changed or even erased! The data generated from some of the best-described paradigms in memory research, in conjunction with powerful neurobiological technologies, have provided striking support for a very dynamic neurobiological basis of memory, which is beginning to overturn the old dogma.

PMID:
12536129
DOI:
10.1016/S0166-2236(02)00042-5
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center