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Microb Drug Resist. 2002 Winter;8(4):329-33.

A clinical strain of Escherichia coli possessing CMY-2 plasmid-mediated amp C beta-lactamase: an emerging concern in pediatrics?

Author information

1
Division of Pediatric Infectious Diseases, Department of Pediatrics, Rainbow Babies and Childrens' Hospital, Cleveland, OH 44106, USA.

Abstract

A 5-year-old child was colonized by an isolate of Escherichia coli that transferred resistance to third-generation cephalosporins and cefoxitin. This resistance phenotype was encoded on a >75-kb plasmid pLRM 22. The transferable plasmid contained both blaCMY-2 and blaTEM-1b. Increasing reports of CMY-2 beta-lactamase in clinical isolates in children raise concerns about the empiric use of third-generation cephalosporins in this patient group.

PMID:
12523630
DOI:
10.1089/10766290260469598
[Indexed for MEDLINE]

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