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Structure. 2003 Jan;11(1):1-2.

Hold tight (but not too tight) to get it right: accurate bypass of an 8-oxoguanine lesion by DNA polymerase beta.

Abstract

Crystal structures of DNA polymerase beta encountering an 8-oxoguanine lesion show how the polymerase selects an otherwise unfavorable conformation of a damaged template base to enable error-free bypass.

PMID:
12517331
DOI:
10.1016/s0969-2126(02)00917-6
[Indexed for MEDLINE]
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