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J Affect Disord. 2003 Jan;73(1-2):105-11.

Impulsivity and phase of illness in bipolar disorder.

Author information

1
Department of Psychiatry, University of Texas Mental Sciences Institute, University of Texas Health Science Center, Houston, TX, USA. alan.c.swann@uth.tmc.edu

Abstract

BACKGROUND:

Impulsivity is prominent in bipolar disorder, but there is little quantitative information relating it to phase of illness.

METHODS:

We measured impulsivity in patients with bipolar disorder who had not met episode criteria for at least 6 months, patients who were manic, and healthy control subjects. Impulsivity was measured using the Barratt Impulsiveness Scale (BIS) and performance on the computerized Immediate Memory-Remote Memory Task (IMT-DMT), based on the Continuous Performance Test, which has been shown to reflect risk of impulsivity in other populations.

RESULTS:

BIS scores in euthymic and manic bipolar subjects were identical, and were significantly elevated compared to controls. Commission errors (impulsive responses) on the IMT-DMT were elevated in manic subjects but were identical to controls in euthymic subjects. Measures of impulsivity did not appear related to depressive symptoms.

LIMITATIONS:

The number of subjects was too small for detailed investigation of the role of comorbidities; subjects were receiving pharmacological treatments.

CONCLUSIONS:

Impulsivity has state- and trait-related aspects in bipolar disorder.

PMID:
12507743
[Indexed for MEDLINE]
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