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J Virol. 2003 Jan;77(2):1571-7.

Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections.

Author information

1
Cirad, Programme Santé Animale, Campus International de Baillarguet, 34398 Montpellier Cedex 05, France.

Abstract

A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against challenge with a virulent PPRV strain.

PMID:
12502870
PMCID:
PMC140790
DOI:
10.1128/jvi.77.2.1571-1577.2003
[Indexed for MEDLINE]
Free PMC Article

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