Dynamic aspects of cadherin-mediated adhesion in synapse development and plasticity

Biol Cell. 2002 Oct;94(6):335-44. doi: 10.1016/s0248-4900(02)00003-5.

Abstract

Cadherins are calcium-dependent cell adhesion molecules that are enriched at synapses. Recent studies indicate important functional roles in synaptic targeting during brain development, and in regulating functional and structural aspects of synaptic plasticity and neural repair throughout life.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain / cytology
  • Cadherins / chemistry
  • Cadherins / physiology*
  • Cell Adhesion*
  • Humans
  • Nerve Regeneration
  • Neurons / cytology
  • Neurons / ultrastructure
  • Synapses / chemistry
  • Synapses / ultrastructure*

Substances

  • Cadherins