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Neurology. 2002 Dec 24;59(12):1971-3.

Improvement of diabetic autonomic gustatory sweating by botulinum toxin type A.

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  • 1Department of Physiological Sciences, University of Catania, Italy.


Fourteen diabetic subjects with gustatory sweating were treated by intracutaneous injections of botulinum toxin type A into the affected facial skin areas. In all subjects, sweating (measured by Minor starch iodine test) ceased within 4 days, with the maximal follow-up time lasting 24 weeks. This therapeutic approach, which could be used to reduce the severity of diabetic gustatory sweating, appears to be long lasting, adverse effect free, and minimally invasive.

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