Olfactory axons: a remarkable convergence

Curr Biol. 2002 Dec 23;12(24):R849-51. doi: 10.1016/s0960-9822(02)01351-9.

Abstract

Thousands of neurons expressing a given mouse odorant receptor project to a few glomeruli in the olfactory bulb. New observations on mice expressing small odorant receptor transgenes provide support for the idea that interdependence is involved in the maturation of this remarkable convergence.

Publication types

  • Review

MeSH terms

  • Animals
  • Axons / physiology*
  • Gene Expression Regulation
  • Green Fluorescent Proteins
  • Luminescent Proteins / genetics
  • Luminescent Proteins / metabolism
  • Mice
  • Mice, Transgenic*
  • Olfactory Bulb / cytology
  • Olfactory Bulb / physiology
  • Olfactory Receptor Neurons / physiology*
  • Receptors, Odorant / genetics
  • Receptors, Odorant / physiology*
  • tau Proteins / genetics
  • tau Proteins / metabolism

Substances

  • Luminescent Proteins
  • Receptors, Odorant
  • tau Proteins
  • Green Fluorescent Proteins