Nasal polyposis in children with cystic fibrosis: a long-term follow-up study

Ann Otol Rhinol Laryngol. 2002 Dec;111(12 Pt 1):1081-6. doi: 10.1177/000348940211101204.

Abstract

The incidence of nasal polyposis among children 5 to 18 years of age with cystic fibrosis (CF) was investigated with a systematic examination of all children on the local CF register. Out of 23 children with CF, 13 had endoscopic evidence of nasal polyposis. Four children had grade 2 polyposis, and 9 children had grade 3 polyposis. Complete opacity of the maxillary sinus was identified on a computed tomographic sinus scan in all but 2 of the children. Only 1 child had a developed frontal sinus. Between 1989 and 2000, 12 children underwent radical endoscopic sinus surgery for their nasal polyposis. There was good postoperative improvement in all of the children; however, 7 eventually required revision surgery because of recurrence of the nasal polyps. The median interval between repeated sinus surgeries was 4 years (range, 18 months to more than 6 years). This information can help in the counseling of parents when sinus surgery is considered for children with CF.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Chronic Disease
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / genetics
  • Endoscopy
  • England / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Nasal Polyps / classification
  • Nasal Polyps / diagnosis
  • Nasal Polyps / epidemiology
  • Nasal Polyps / etiology*
  • Nasal Polyps / surgery
  • Patient Education as Topic
  • Recurrence
  • Registries
  • Reoperation
  • Rhinitis / classification
  • Rhinitis / diagnosis
  • Rhinitis / epidemiology
  • Rhinitis / etiology*
  • Rhinitis / surgery
  • Severity of Illness Index
  • Sinusitis / classification
  • Sinusitis / diagnosis
  • Sinusitis / epidemiology
  • Sinusitis / etiology*
  • Sinusitis / surgery
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome