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Nature. 2002 Dec 19-26;420(6917):875-8.

Mast cells in autoimmune disease.

Author information

  • 1Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA. cbdm@joslin.harvard.edu

Abstract

Mast cells are known to be the primary responders in allergic reactions, orchestrating strong responses to minute amounts of allergens. Several recent observations indicate that they may also have a key role in coordinating the early phases of autoimmune diseases, particularly those involving auto-antibodies.

PMID:
12490961
DOI:
10.1038/nature01324
[PubMed - indexed for MEDLINE]
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