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NMR Biomed. 2002 Nov-Dec;15(7-8):570-7.

Applications of diffusion-weighted and diffusion tensor MRI to white matter diseases - a review.

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Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, UK.


This paper reviews the current applications of diffusion-weighted and diffusion tensor MRI in diseases of the brain white matter. The contribution that diffusion-weighted imaging has made to our understanding of white matter diseases is critically appraised. The quantitative nature of diffusion MRI is one of its major attractions; however, this is offset by the more advanced hardware required to collect diffusion-weighted images reliably, and the more complex processing to produce quantitative parametric diffusion images. With the now common availability of scanners equipped to perform echo-planar imaging, the acquisition of diffusion tensor images is sure to become more widespread and routine.

[Indexed for MEDLINE]

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