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Ann Oncol. 2003 Jan;14(1):74-7.

Results of interval debulking surgery in advanced stage ovarian cancer: an exposed-non-exposed study.

Author information

1
Department of Surgery, Institut Gustave Roussy, Villejuif, France. morice@igr.fr

Abstract

BACKGROUND:

To study the results of interval debulking surgery (IDS) in patients treated for 'unresectable' advanced stage ovarian cancer compared with primary debulking surgery (PDS) followed by chemotherapy.

PATIENTS AND METHODS:

An exposed-non-exposed study including a group of 34 patients who underwent an IDS and were matched to an historic control group of 34 patients treated with PDS.

RESULTS:

Optimal cytoreductive surgery was achieved in 94% (32 out of 34) of patients in both groups. The rates of post-operative morbidity, blood transfusion and median length of hospitalisation were significantly reduced in the study (IDS) group, but survival did not differ in both groups.

CONCLUSIONS:

IDS in patients with advanced stage ovarian cancer offers the same chance of survival as PDS, but it is better tolerated.

PMID:
12488296
DOI:
10.1093/annonc/mdg003
[Indexed for MEDLINE]
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