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Masui. 2002 Nov;51(11):1248-50.

[Successful intravenous administration of low dose ketamine for pain caused by erythromelalgia: report of a case].

[Article in Japanese]

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Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113-8655.


A 15-year-old female complained of reddening, edema, and pain in her hands and feet. The symptoms were relieved upon cooling. From these findings, a diagnosis of erythromelalgia was made. Because none of the oral medication prescribed by dermatologist was effective, the patient was consulted to our department. A low dose of ketamine, a drug considered to be effective for intractable pain, was administered intravenously and the pain subsided significantly. Furthermore, the pain became completely controllable with a combination of intramuscular ketamine injection and other oral medication.

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