Format

Send to

Choose Destination
See comment in PubMed Commons below
Appl Opt. 2002 Dec 1;41(34):7325-33.

Adaptive calibration for object localization in turbid media with interfering diffuse photon density waves.

Author information

1
Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. chenyu@mail.med.upenn.edu

Abstract

The amplitude cancellation method that uses dual out-of-phase sources (a phased array system) can sensitively detect and locate small objects in turbid media. The balance of these two sources is crucial to the system's detection sensitivity and accuracy. We describe a convenient method with which to adaptively calibrate the amplitudes of the two sources at each scanning position by use of low-frequency modulation of the intensity of the in-phase and the antiphase sources. We achieve accurate localization ability of the phased array system by accounting for the influence of asymmetrical boundaries and the heterogeneous background absorption. Experimental data on human breast phantoms demonstrate that localization accuracy within several millimeters has been accomplished through this method.

PMID:
12477125
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Optical Society of America
    Loading ...
    Support Center