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Trends Plant Sci. 2002 Dec;7(12):531-4.

Transcription factors do it together: the hows and whys of studying protein-protein interactions.

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  • 1Business Unit Plant Development and Reproduction, Plant Research International, Bornsesteeg 65, 6708 PD Wageningen, The Netherlands.


Protein-protein interactions are intrinsic to virtually every cellular process. Recent breakthroughs in techniques to study protein-interaction and the availability of fully sequenced plant genomes have attracted many plant scientists to undertake the first steps in the field of protein interactions. High-throughput screening systems allow the discovery of protein functions. Even without performing laborious functional assays, in planta functional homologues and redundant proteins can be accurately predicted based on protein-interaction maps. Therefore, protein-protein-interaction screenings are an essential supplement to the current functional-genomics toolbox.

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