Format

Send to

Choose Destination
See comment in PubMed Commons below
Cell Mol Life Sci. 2002 Oct;59(10):1658-65.

A specialized mitochondrial molecular chaperone system: a role in formation of Fe/S centers.

Author information

1
Department of Biomolecular Chemistry, 1300 University Avenue, University of Wisconsin, Madison, Wisconsin 53706, USA. ecraig@facstaff.wisc.edu

Abstract

Mitochondria contain a specialized system of molecular chaperones that plays a critical role in the biogenesis of Fe/S centers. This Hsp70:J-protein system shows many similarities to the system found in bacteria, but the precise role of neither chaperone system has been defined. However, evidence to date suggests an interaction with the scaffold protein on which a transient Fe/S center is assembled, and thus implies a role in either assembly of the center or its transfer to recipient proteins.

PMID:
12475176
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center