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Curr Opin Cell Biol. 2002 Dec;14(6):734-8.

Engulfment mechanism of apoptotic cells.

Author information

1
Cutaneous Biology Research Center, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.

Abstract

Apoptotic cells are engulfed and removed by phagocytes. This ensures proper development of the organism and can modulate immune responses. Recent studies have examined molecules on apoptotic cells, such as phosphatidylserine, which may signal for engulfment through multiple receptors. Apoptotic recognition mechanisms may vary with the apoptotic and engulfing cell type, and even with the age of the corpse.

PMID:
12473347
DOI:
10.1016/s0955-0674(02)00390-3
[Indexed for MEDLINE]

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