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Behav Genet. 2002 Nov;32(6):435-43.

Food intake, water intake, and drinking spout side preference of 28 mouse strains.

Author information

1
Monell Chemical Senses Center, 3500 Market St., Philadelphia, Pennsylvania 19104, USA. bachmanov@monell.org

Abstract

Male mice from 28 inbred strains (129P3/J, A/J, AKR/J, BALB/cByJ, BUB/BnJ, C3H/HeJ, C57BL/6J, C57L/J, CAST/Ei, CBA/J, CE/J, DBA/2J, FVB/NJ, I/LnJ, KK/H1J, LP/J, NOD/LtJ, NZB/B1NJ, P/J, PL/J, RBF/DnJ, RF/J, RIIIS/J, SEA/GnJ, SJL/J, SM/J, SPRET/Ei, and SWR/J) were fed chow and had access to two water bottles. Body weight, food intake, water intake, and drinking spout side preference were measured. There were large strain differences in all the measures collected, with at least a two-fold difference between strains with the lowest and the highest trait values. Estimates of heritability ranged from 0.36 (spout side preference) to 0.87 (body weight). Body weight, food intake, and water intake were interrelated among the strains, although substantial strain variation in food and water intakes independent from body weight was present. The strain differences described here provide useful information for designing mutagenesis screens and choosing strains for genetic mapping studies.

PMID:
12467341
PMCID:
PMC1397713
DOI:
10.1023/a:1020884312053
[Indexed for MEDLINE]
Free PMC Article

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