Format

Send to

Choose Destination
Mov Disord. 2002 Nov;17(6):1271-7.

Phenomenology of "Lubag" or X-linked dystonia-parkinsonism.

Author information

1
Department of Neurology, Mayo Clinic, Scottsdale, Arizona 85259, USA. evidente.virgilio@mayo.edu

Abstract

X-linked dystonia-parkinsonism (XDP), or Lubag syndrome, is known to cause progressive dystonia, with or without parkinsonism, among Filipino male adults with maternal roots from the Philippine island of Panay. We present cinematographic material of 11 cases of Lubag carrying the XDP haplotypes who manifest with a wide spectrum of movement disorders, including dystonia, tremor, parkinsonism, myoclonus, chorea, and myorhythmia. Because of overlapping features, Lubag patients are commonly misdiagnosed as idiopathic dystonia, essential tremor, Parkinson's disease, or Parkinson's-plus syndromes. Thus, it is imperative to elicit an exhaustive family history in any Filipino male adult who presents with a movement disorder.

PMID:
12465067
DOI:
10.1002/mds.10271
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center