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Eur J Dermatol. 2002 Nov-Dec;12(6):609-11.

Localized argyria 20-years after embedding of acupuncture needles.

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Department of Dermatology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Japan.


We report a 66-year-old woman with localized argyria caused by embedding of acupuncture needles. Ten years after she had received acupuncture, she noticed two asymptomatic bluish macules on her right arm. A biopsied specimen from the macule revealed many brownish-black granules mainly located around the sweat glands and the blood vessels in the dermis. The X-ray examination of the extremities revealed numerous needle-like fragments around her extremities. "Embedding of needles" induces some serious adverse events. We should know the adverse events for the safety and health of patients.

[Indexed for MEDLINE]

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