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Res Microbiol. 2002 Nov;153(9):557-62.

Role of the RNA polymerase sigma subunit in transcription initiation.

Author information

1
SUNY Health Sciences Center at Brooklyn, Brooklyn, NY 11203, USA.

Abstract

In bacteria, sigma subunits direct the catalytically competent RNA polymerase core enzyme to promoters. Recent advances in our understanding of bacterial RNA polymerase reveal that sigma subunits are intimately involved in all aspects of transcription initiation including promoter location, promoter melting, initiation of RNA synthesis, abortive initiation and promoter escape.

PMID:
12455702
DOI:
10.1016/s0923-2508(02)01368-2
[Indexed for MEDLINE]

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