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J Alzheimers Dis. 2002 Aug;4(4):303-8.

Head trauma and Alzheimer's disease.

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Department of Neurology, Vrije Universiteit Medical Centre, Amsterdam, the Netherlands.


The authors describe a case of a 55 year old woman who was diagnosed with Alzheimer's disease 1.5 years after a car accident in which she experienced a mild concussion. Extensive history taking disclosed no cognitive changes prior to the car accident. The case is discussed in view of the inflammation hypothesis regarding Alzheimer's disease and the role of the apolipoprotein E4 genotype of the patient.

[Indexed for MEDLINE]

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