Interobserver and intraobserver variability of measurements of uveal melanomas using standardised echography

Br J Ophthalmol. 2002 Dec;86(12):1390-4. doi: 10.1136/bjo.86.12.1390.

Abstract

Aims: To report on the intraindividual and interindividual variability of tumour size (height and base diameter) measurements using standardised echography in a masked prospective study.

Methods: 20 consecutive eyes of 20 patients were examined on four different visits by three experienced examiners using standardised echography. As common in standardised echography, tumour height was evaluated with A-scan technique, while transverse and longitudinal base diameter were calculated with B-scan.

Results: Tumour height measurements using A-scan were more accurate than base diameter measurements using B-scan. The standard deviation for tumour height over all visits/measurements was 0.18 mm (A-scan), 0.79 mm for transverse, and 0.69 mm for longitudinal base diameters (B-scan). The interclass correlation coefficient (ICC) was much higher for tumour height measurements with A-scan (0.7735 for three examiners on one visit) than for transverse (0.6563) or longitudinal (0.4522) base diameter measurements with B-scan techniques.

Conclusions: A-scan techniques for tumour height measurements provide very reproducible results with little intraindividual and interobserver variability. As B-scan techniques for tumour base evaluation are less accurate they should be used for topographic and morphological examinations.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Melanoma / diagnostic imaging*
  • Melanoma / pathology
  • Middle Aged
  • Observer Variation
  • Prospective Studies
  • Reproducibility of Results
  • Ultrasonography
  • Uveal Neoplasms / diagnostic imaging*
  • Uveal Neoplasms / pathology