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Protein Sci. 2002 Dec;11(12):2894-8.

Prediction of novel archaeal enzymes from sequence-derived features.

Author information

1
Center for Biological Sequence Analysis, BioCentrum-DTU, The Technical University of Denmark, DK-2800 Lyngby, Denmark.

Abstract

The completely sequenced archaeal genomes potentially encode, among their many functionally uncharacterized genes, novel enzymes of biotechnological interest. We have developed a prediction method for detection and classification of enzymes from sequence alone (available at http://www.cbs.dtu.dk/services/ArchaeaFun/). The method does not make use of sequence similarity; rather, it relies on predicted protein features like cotranslational and posttranslational modifications, secondary structure, and simple physical/chemical properties.

PMID:
12441387
PMCID:
PMC2373754
DOI:
10.1110/ps.0225102
[Indexed for MEDLINE]
Free PMC Article

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