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Ann N Y Acad Sci. 2002 Oct;971:248-50.

The role of different Scinderin domains in the control of F-actin cytoskeleton during exocytosis.

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Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.


Scinderin (Sc), a Ca(2+)-regulated actin-binding protein, has been previously shown to control submembranous actin dynamics in regulated secretion. The results of the present study suggest the possibility that Sc might act as a molecular switch in the control of cortical F-actin dynamics during secretion.

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