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Nature. 2002 Nov 14;420(6912):246-51.

The community of the self.

Author information

  • 1Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110-1093, USA. buchman@msnotes.wustl.edu

Abstract

Good health, which reflects the harmonious integration of molecules, cells, tissues and organs, is dynamically stable: when displaced by disease, compensation and correction are common, even without medical care. Physiology and computational biology now suggest that healthy dynamic stability arises through the combination of specific feedback mechanisms and spontaneous properties of interconnected networks. Today's physicians are already testing to 'see if the network is right'; tomorrow's physicians may well use therapies to 'make the network right'.

PMID:
12432410
DOI:
10.1038/nature01260
[PubMed - indexed for MEDLINE]
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