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Int J Antimicrob Agents. 2002 Nov;20(5):390-2.

In vitro investigation of the susceptibility of Acinetobacter baumannii strains isolated from clinical specimens to ampicillin/sulbactam alone and in combination with amikacin.

Author information

1
Military Medical Academy (MMA), Sofia, Bulgaria. savove@yahoo.com

Abstract

The sensitivity of 52 strains of Acinetobacter baumannii was determined to 13 antimicrobial drugs. All strains tested were multiresistant. Compared with MICs of amikacin and ampicillin/sulbactam alone, there was a significant decrease in MICs for both drugs when the combination was used. The results of the in vitro study of this combination showed a synergistic or partial synergistic effect in 98% of the strains.

PMID:
12431877
DOI:
10.1016/s0924-8579(02)00207-8
[Indexed for MEDLINE]

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