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Bioinformatics. 2002 Nov;18(11):1544-5.

Poxvirus Orthologous Clusters (POCs).

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Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8W 3P6, Canada.


Poxvirus Orthologous Clusters (POCs) is a JAVA client-server application which accesses an updated database containing all complete poxvirus genomes; it automatically groups orthologous genes into families based on BLASTP scores for assessment by a human database curator. POCs has a user-friendly interface permitting complex SQL queries to retrieve interesting groups of DNA and protein sequences as well as gene families for subsequent interrogation by a variety of integrated tools: BLASTP, BLASTX, TBLASTN, Jalview (multiple alignment), Dotlet (Dotplot), Laj (local alignment), and NAP (nucleotide to amino acid alignment).

[Indexed for MEDLINE]

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