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Org Lett. 2002 Nov 14;4(23):4089-92.

Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia.

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Department of Chemistry, University of British Columbia, Vancouver, B.C., V6T 1Z1, Canada.


Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.[structure: see text].

[Indexed for MEDLINE]

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