Format

Send to

Choose Destination
Cell. 2002 Nov 1;111(3):281-4.

Epigenetic consequences of nucleosome dynamics.

Author information

1
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA.

Abstract

Current models for epigenetic gene silencing envision a static relationship between histone modifications and transcription. However, evidence for nucleosome mobility and replacement favors a dynamic model that may explain phenomena ranging from variegation to the neural restriction of Rett syndrome.

PMID:
12419239
DOI:
10.1016/s0092-8674(02)01081-4
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center