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Mol Cell. 2002 Oct;10(4):693-5.

Two pathways to NF-kappaB.

Author information

1
Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

NF-kappaB is a transcription factor that is critical for innate and adaptive immunity. Recently, a noncanonical pathway for NF-kappaB activation has emerged. Four recent papers provide physiological roles for this pathway and expand our understanding of lymphoid development and organogenesis with potential applications in the treatment of autoimmune disease.

PMID:
12419209
DOI:
10.1016/s1097-2765(02)00697-4
[Indexed for MEDLINE]
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