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MMWR Morb Mortal Wkly Rep. 2002 Oct 11;51(40):902.

Vancomycin-resistant Staphylococcus aureus--Pennsylvania, 2002.

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  • MMWR Morb Mortal Wkly Rep 2002 Oct 18;51(41):931.


Staphylococcus aureus is one of the most common causes of hospital- and community-acquired infections. Since the recognition of vancomycin-resistant enterococci in 1988, the emergence of vancomycin-resistant S. aureus (VRSA) (minimum inhibitory concentration [MIC] > or = 32 microg/mL) has been anticipated. The transfer of the genetic element containing the vanA vancomycin resistance gene from Enterococcus faecalis to S. aureus was demonstrated in the laboratory in 1992; the first clinical infection with VRSA was reported in July 2002. This report describes the second documented clinical isolate of VRSA from a patient.

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