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Vet Microbiol. 2002 Dec 20;90(1-4):587-92.

The genome of Brucella melitensis.

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Institute of Molecular Biology and Medicine, University of Scranton, Scranton, PA 18510, USA.


The genome of Brucella melitensis strain 16M was sequenced and contained 3,294,931 bp distributed over two circular chromosomes. Chromosome I was composed of 2,117,144 bp and chromosome II has 1,177,787 bp. A total of 3,198 ORFs were predicted. The origins of replication of the chromosomes are similar to each other and to those of other alpha-proteobacteria. Housekeeping genes such as those that encode for DNA replication, protein synthesis, core metabolism, and cell-wall biosynthesis were found on both chromosomes. Genes encoding adhesins, invasins, and hemolysins were also identified.

[Indexed for MEDLINE]

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