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Mol Cell. 2002 Sep;10(3):439-40.

Duplicating dangerously: linking centrosome duplication and aneuploidy.

Author information

1
Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Abstract

Centrosomes are far more fascinating than the first explorers of this organelle a century ago could ever have imagined. Recent evidence indicates that deregulation of centrosome duplication affects centrosome number and promotes aneuploidy, features characteristic of human tumors.

PMID:
12408813
DOI:
10.1016/s1097-2765(02)00654-8
[Indexed for MEDLINE]
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