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Muscle Nerve. 2002 Nov;26(5):708-12.

Inhibition of maximal voluntary contraction force by experimental muscle pain: a centrally mediated mechanism.

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Center for Sensory-Motor Interaction, Laboratory for Experimental Pain Research, Aalborg University, Fredrik Bajers Vej 7D-3, DK-9220 Aalborg E, Denmark.


Muscle weakness frequently accompanies conditions with musculoskeletal pain. It is not clear if this attenuation of force is due to peripheral or central processes. The effect of experimental muscle pain on maximal voluntary contraction torque and peripheral contractile properties was therefore assessed. Experimental muscle pain reduced the torque produced by isometric knee extension, but the contractile properties assessed by twitch interpolation were not affected. This indicates that force inhibition by muscle pain is centrally mediated. This has clinical implications for rehabilitation and training of patients with musculoskeletal pain.

[Indexed for MEDLINE]

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