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Ann Neurol. 2002 Nov;52(5):647-50.

Vitamin A in the cerebrospinal fluid of patients with and without idiopathic intracranial hypertension.

Author information

1
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Health Sciences Center, 50 North Medical Drive, Salt Lake City, UT 84132, USA. judith.warner@hsc.utah.edu

Abstract

We quantified vitamin A in the cerebrospinal fluid of patients with idiopathic intracranial hypertension, elevated intracranial pressure of other causes and normal intracranial pressure. Vitamin A could be detected by high-pressure liquid chromatography in most of the specimens. There was a significantly higher level of vitamin A in the cerebrospinal fluid of some patients with idiopathic intracranial hypertension. Vitamin A toxicity may play a role in the pathogenesis of idiopathic intracranial hypertension.

PMID:
12402264
DOI:
10.1002/ana.10377
[Indexed for MEDLINE]

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