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Science. 2002 Oct 25;298(5594):781-5.

Emerging roles of presynaptic proteins in Ca++-triggered exocytosis.

Author information

1
Department of Physiology, Saarland University, Homburg, 66421 Germany. jrettig@uniklinik-saarland.de

Erratum in

  • Science 2002 Nov 15;298(5597):1336.

Abstract

The twinning of techniques from biophysics and molecular biology has led to remarkable progress in understanding the molecular mechanisms of synaptic transmission. Here we review the current picture of Ca++-triggered exocytosis, which has emerged from studies of a simple cellular model, the adrenal chromaffin cell. We discuss the molecular players that have been assigned a specific role in a particular step of this process and give a brief outlook on what these insights might tell us about mechanisms of short-term plasticity at classical synapses.

PMID:
12399579
DOI:
10.1126/science.1075375
[Indexed for MEDLINE]

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