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Trends Plant Sci. 2002 Oct;7(10):425-7.

The Arabidopsis RRS1-R disease resistance gene--uncovering the plant's nucleus as the new battlefield of plant defense?

Abstract

The isolation of over 30 plant disease-resistance genes revealed that most genes encode putatively cytoplasmic proteins with a nucleotide-binding site (NBS) and a leucine-rich repeat (LRR). However, the recent isolation of the Arabidopsis RRS1-R gene has uncovered a novel NBS-LRR subtype that harbors a C-terminal extension with a putative nuclear localization signal and a DNA-binding domain that is characteristic of the WRKY transcription factor family. This suggests that RRS1-R, unlike any other known R protein, is targeted to the nucleus to fulfill its function.

PMID:
12399170
DOI:
10.1016/s1360-1385(02)02334-8
[Indexed for MEDLINE]

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