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J Neurosci Res. 2002 Nov 1;70(3):357-60.

Role of mitochondrial dysfunction in Alzheimer's disease.

Author information

1
Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA. rjc8@po.cwru.edu

Abstract

Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to this disease.

PMID:
12391597
DOI:
10.1002/jnr.10389
[Indexed for MEDLINE]

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