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Rheum Dis Clin North Am. 2002 Aug;28(3):561-77, vi-vii.

Systemic lupus erythematosus in childhood.

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Division of Immunology/Rheumatology, Department of Pediatrics, Children's Memorial Hospital, Northwestern University, Chicago, IL, USA.


Systemic lupus erythematosus is a disease of immune dysregulation that strikes approximately 1 in 2000 individuals. The usual patient is a young woman of child-bearing age; however, this illness affects patients of all ages, ethnic backgrounds, and both sexes. Twenty percent of all cases of lupus are diagnosed during the first two decades of life. Perhaps the most essential point in treating a child with lupus is to be aware and concerned about how to deliver treatment to a patient in the middle of their physical, intellectual, and emotional development.

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