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Eur J Paediatr Neurol. 2002;6(4):221-3.

Frequent seizures with elevated interleukin-6 at the eruptive stage of exanthema subitum.

Author information

1
Department of Paediatrics, Otsu Red Cross Hospital, Otsu, Japan. masumigo@mbox.kyoto-inet.or.jp

Abstract

A 15-month-old girl developed frequent seizures at the eruptive stage of exanthema subitum. The eruption persisted for 2 weeks. Serum immunoglobulin G antibody to human herpes virus type 6 (HHV-6) increased markedly. Interleukin-6 was elevated whereas HHV-6 deoxyribonucleic acid was not detected in cerebrospinal fluid. These findings suggest that immune-mediated reactions after HHV-6 infection rather than direct action of active HHV-6 are responsible for frequent seizures in this case.

PMID:
12374589
DOI:
10.1053/ejpn.2002.0597
[Indexed for MEDLINE]

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