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Curr Biol. 2002 Sep 17;12(18):R618-9.

Centriole duplication: centrin in on answers?

Author information

1
Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA.

Abstract

Many aspects of centriole biology remain mysterious. A new study has shed light on the role of the centriolar protein centrin-2: reducing levels of centrin-2 in HeLa cells has been found to block centriole duplication, eventually leading to cell death.

PMID:
12372266
DOI:
10.1016/s0960-9822(02)01133-8
[Indexed for MEDLINE]
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