Format

Send to

Choose Destination
Genome Biol. 2002 Sep 16;3(10):reviews1027. Epub 2002 Sep 16.

Large-scale gene-expression studies and the challenge of multiple sclerosis.

Author information

1
Department of Neurology, University of California San Francisco, San Francisco, CA 94143-0435, USA. sebaran@cgl.ucsf.edu

Abstract

In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage. Recent transcription-profiling studies have found distinct gene-expression patterns in diseased tissue; such large-scale studies at different stages of the disease are contributing to understanding multiple sclerosis and developing effective therapy.

PMID:
12372148
PMCID:
PMC244911
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center