Format

Send to

Choose Destination
J Clin Virol. 2002 Aug;25(2):193-5.

Encephalomyelitis due to human parechovirus type 1.

Author information

1
Centre National de Reference pour les Enterovirus et L'hepatite A Laboratoire de Virologie, Domaine Rockefeller, Lyon, France.

Abstract

OBJECTIVES:

The implication of a viral agent in encephalomyelitis has been reported for several years. In the present study we wanted to demonstrate the presence of human parechovirus type 1 (HPEV1) in a patient diagnosed with encephalomyelitis.

STUDY DESIGN:

Clinical samples (throat and rectal swabs, acute and convalescent sera, cerebrospinal fluid) were collected from a 10-month-old boy diagnosed with encephalomyelitis. The appropriated samples were tested for cytomegalovirus, varicella zona virus, mumps virus and enteroviruses with specific culture, and serological and molecular biological techniques.

RESULTS:

HPEV1 was isolated from the throat and its genome was additional detectable in the cerebrospinal fluid, throat swab and acute serum. The samples were negative for all other tested viruses.

CONCLUSION:

To our knowledge, this is the first reported case of HPEV1 infection related to encephalomyelitis. This emphasis that human parechoviruses can be responsible for severe central nervous system infections in children.

PMID:
12367654
DOI:
10.1016/s1386-6532(02)00009-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center