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Curr Opin Neurobiol. 2002 Oct;12(5):508-15.

The formation of sensorimotor circuits.

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  • 1Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Rd, La Jolla, California 92037, USA.


Recent studies have identified some of the key molecular pathways that control the genesis of spinal sensorimotor circuits. Transcription factors play a central role in these events, regulating both the specification of neurons that constitute these sensorimotor pathways and the expression of downstream molecules that control the wiring up of these neurons into topologically interconnected neuronal networks.

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